![]() SOMIT combines a tolerance-inducing agent with targeted delivery of specific antigens to the oral mucosa, an immune-priviliged target. Allero’s vision is to improve the quality of life and survival of these patients and to achieve this, Allero is developing a next generation proprietary immunotherapy approach SOMIT (Specific Oromucosal Immunotherapy). Current therapy of immune mediated disorders remains unsatisfactory as they either do not treat the underlying causes and have significant side effects (autoimmune), or efficacy and compliance is poor (allergy). Immune mediated disorders refer to a broad range of conditions such as autoimmune and allergic diseases which result from abnormal activity of the body’s immune system upon exposure to innocuous triggers which may lead the immune system to over-react or start attacking the body. The Pintuition Probe is reusable, robust and very simple to use.Īllero Therapeutics is a biopharmaceutical company that develops next generation immunotherapies for immune mediated disorders. The system is CE-approved and clinically validated. ![]() The Sirius Pintuition provides directional and intuitive localization with millimeter accurate real-time distance feedback, allowing surgeons to remove non-palpable tumors with minimal resection margin and optimal clinical result. Not only a better clinical outcome due to improved accuracy, but also much simpler in practical use because there is no radio-activity involved and it’s time-saving for radiologists. This next-generation tumor localization technique provides surgeons with significant benefits over existing methods. They recognized the need and opportunity to simplify and improve the localization technology for the surgical removal of breast cancers, ultimately resulting in the proprietary Sirius Pintuition technology, comprised of a detector, probe and magnetic marker seed. By co-founding Curie Capital in 2018 Mariette uses her broad knowledge and experience in the Life Sciences field to invest in early stage start-ups.Īs a spin-off from the Netherlands Cancer Institute, Sirius Medical has its roots embedded in the surgical clinic for cancer treatment. In 2017 Mariette founded Curiant, through which she gives investment related consultancy to early stage companies and investors within the field of Life Sciences. ![]() This includes being highly involved in many innovative start-up ventures and the international launch of innovative products. Before working as a Life Science investor, Mariette had 17 years of all round management and business development experience in biotech. Here Mariette was responsible for the management of up to 13 portfolio companies where she represented the BOM as shareholder and, to a number of these companies, as Board Member. From 2013 until 2018 Mariette was Senior Investment Manager Life Sciences & Health at the Brabantse Ontwikkelings Maatschappij (BOM). During these years Mariette gained in depth experience and expertise in the field through a broad range of companies and products. Mariette has an extensive background in the field of Life Sciences as she has 23 years of experience working for and with international companies developing and selling new medical technologies and medicines. Since 2017 Han is also an active investor in the field of Life Sciences and by co-founding Curie Capital in 2018 he looks to expand his activities in this fast developing field. Han is also founder of VOC Capital Partners and Stadswaarde through which he invests in technology related companies and real estate respectively. Han remained Board Member until late 2016 and shareholder until the company went public on the Tokyo Stock Exchange in 2017. After the merger the companies continued under the ‘Macromill Group’ brand of which Han became global CEO until late 2015. In 2014 Han merged MetrixLab with MacroMill into a leading marketing tech company with +300M in annual revenue, 1800 employees and 30 offices worldwide. To speed up MetrixLab’s growth he successfully executed six acquisitions. ![]() Han founded MetrixLab in 1999 and expanded the company into multiple countries in- and outside of Europe. Han has a background of leading a consumer intelligence company called MetrixLab from start to public exit as founder, CEO and Board Member.
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